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Takashi Kanbayashi Selected Research

Cataplexy

1/2021Induction of narcolepsy-like symptoms by orexin receptor antagonists in mice.
12/2018A variant at 9q34.11 is associated with HLA-DQB1*06:02 negative essential hypersomnia.
1/2018Continuous intrathecal orexin delivery inhibits cataplexy in a murine model of narcolepsy.
2/2015New susceptibility variants to narcolepsy identified in HLA class II region.
1/2015An association analysis of HLA-DQB1 with narcolepsy without cataplexy and idiopathic hypersomnia with/without long sleep time in a Japanese population.
11/2014Noninvasive detection of sleep/wake changes and cataplexy-like behaviors in orexin/ataxin-3 transgenic narcoleptic mice across the disease onset.
9/2012Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy.
4/2011The pathophysiologic basis of secondary narcolepsy and hypersomnia.
5/2010Hypocretin ligand deficiency in narcolepsy: recent basic and clinical insights.
6/2009[Recent advance of treatments for narcolepsy and hypersomnia].
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Takashi Kanbayashi Research Topics

Disease

37Narcolepsy
04/2022 - 03/2002
37Disorders of Excessive Somnolence (Hypersomnia)
10/2020 - 07/2002
20Cataplexy
01/2021 - 03/2002
8Sleepiness
02/2020 - 08/2011
7Idiopathic Hypersomnia
04/2022 - 03/2002
6Encephalitis (Encephalitis, Rasmussen)
05/2021 - 07/2007
5Neuromyelitis Optica (Devic's Disease)
08/2019 - 04/2011
4Sleep Initiation and Maintenance Disorders (Insomnia)
01/2022 - 06/2002
4Schizophrenia (Dementia Praecox)
01/2018 - 05/2012
4Nervous System Diseases (Neurological Disorders)
01/2018 - 08/2005
3Anti-N-Methyl-D-Aspartate Receptor Encephalitis
02/2022 - 01/2019
3Dementia (Dementias)
01/2021 - 12/2006
3Alzheimer Disease (Alzheimer's Disease)
01/2020 - 06/2002
3Infarction (Infarctions)
08/2019 - 08/2005
3Catatonia
01/2019 - 01/2014
3Treatment-Resistant Schizophrenia
08/2018 - 02/2016
3Epilepsy (Aura)
01/2018 - 03/2002
3Sleep Paralysis
01/2018 - 03/2002
3Obesity
05/2016 - 03/2011
3Demyelinating Diseases (Demyelinating Disease)
12/2009 - 08/2005
3Parkinson Disease (Parkinson's Disease)
05/2009 - 12/2006
3Brain Diseases (Brain Disorder)
02/2009 - 08/2005
3Multiple Sclerosis
07/2004 - 06/2002
2Kleine-Levin Syndrome (Syndrome, Kleine-Levin)
01/2022 - 01/2018
2Psychotic Disorders (Schizoaffective Disorder)
05/2021 - 01/2014
2Sleep Wake Disorders
10/2020 - 02/2015
2Psychomotor Agitation (Akathisia)
08/2018 - 01/2018
2Myotonic Dystrophy (Dystrophia Myotonica)
01/2018 - 07/2009
2Coma (Comas)
07/2016 - 01/2014
2Sleep Deprivation
11/2014 - 12/2003
2Inappropriate ADH Syndrome (SIADH)
01/2014 - 08/2011
2Guillain-Barre Syndrome
12/2012 - 06/2002
2Craniocerebral Trauma (Head Injury)
02/2009 - 08/2005
2Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
12/2006 - 12/2003
2Hypothalamic Neoplasms
09/2006 - 12/2004
2Acute Disseminated Encephalomyelitis (Postinfectious Encephalomyelitis)
11/2004 - 07/2002
1Inflammation (Inflammations)
10/2022
1Autoimmune Diseases of the Nervous System
05/2021
1Dissociative Disorders (Fugue)
05/2021
1Muscle Weakness
10/2020
1Autoimmune Diseases (Autoimmune Disease)
10/2020
1Carcinosarcoma
10/2020
1Leukocytosis (Pleocytosis)
08/2019
1Oculomotor Nerve Diseases (Oculomotor Nerve Palsy)
08/2019
1Lymphoma (Lymphomas)
06/2019
1Mood Disorders (Mood Disorder)
01/2019
1Disease Progression
01/2019
1Apnea
01/2018
1Traumatic Brain Injuries (Traumatic Brain Injury)
01/2018
1Delirium
01/2018
1Hallucinations (Hallucination)
01/2018
1Pancytopenia
01/2018
1Sleep Apnea Syndromes (Sleep Apnea)
01/2018
1Circadian Rhythm Sleep Disorders (Delayed Sleep Phase Syndrome)
01/2018

Drug/Important Bio-Agent (IBA)

54OrexinsIBA
04/2022 - 03/2002
6N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
05/2021 - 05/2012
6AntibodiesIBA
06/2019 - 04/2011
6HLA Antigens (Human Leukocyte Antigens)IBA
12/2018 - 11/2003
5Clozapine (Clozaril)FDA LinkGeneric
08/2018 - 11/2013
5Pharmaceutical PreparationsIBA
12/2014 - 06/2002
4HLA-DQB1 antigen (HLA DQB1)IBA
10/2020 - 01/2015
4anti-aquaporin 4 autoantibodyIBA
10/2012 - 02/2009
4SteroidsIBA
10/2012 - 02/2009
3Immunoglobulin G (IgG)IBA
08/2019 - 04/2011
3LigandsIBA
05/2010 - 08/2005
2Aripiprazole (Abilify)FDA Link
10/2021 - 01/2018
2AntigensIBA
10/2020 - 06/2002
2Methylphenidate (Ritalin)FDA LinkGeneric
02/2020 - 06/2009
2Proteins (Proteins, Gene)FDA Link
08/2019 - 01/2018
21- (((alpha- isobutanoyloxyethoxy)carbonyl)aminomethyl)- 1- cyclohexaneacetic acidIBA
08/2018 - 01/2018
2Antipsychotic Agents (Antipsychotics)IBA
01/2018 - 01/2018
2N 30IBA
01/2018 - 08/2005
2Anticonvulsants (Antiepileptic Drugs)IBA
06/2015 - 01/2014
2Vasopressins (Vasopressin)IBA
01/2014 - 08/2011
2MethylprednisoloneFDA LinkGeneric
01/2014 - 08/2003
2Aquaporin 4IBA
01/2012 - 04/2011
2Histamine (Histamine Dihydrochloride)FDA Link
06/2009 - 02/2009
2Adrenal Cortex Hormones (Corticosteroids)IBA
08/2005 - 07/2002
1Sevoflurane (Ultane)FDA LinkGeneric
10/2022
1LipopolysaccharidesIBA
10/2022
1LithiumIBA
01/2022
1Hypnotics and Sedatives (Sedatives)IBA
01/2022
1Rituximab (Mabthera)FDA Link
05/2021
1suvorexantIBA
01/2021
1Orexin Receptor AntagonistsIBA
01/2021
1Immune Checkpoint InhibitorsIBA
10/2020
1pembrolizumabIBA
10/2020
1Clopidogrel (Plavix)FDA Link
08/2019
1EdaravoneIBA
08/2019
1argatroban (MPQA)FDA Link
08/2019
1BenzodiazepinesIBA
08/2018
1Biperiden (Akineton)FDA Link
08/2018
1perampanelIBA
01/2018
1Gabapentin (Neurontin)FDA LinkGeneric
01/2018
1ProdrugsIBA
01/2018

Therapy/Procedure

8Therapeutics
10/2020 - 08/2005
4Immunotherapy
02/2022 - 02/2016
4Aftercare (After-Treatment)
01/2020 - 12/2012
1Nursing Care
01/2020
1Drug Therapy (Chemotherapy)
06/2019